December 21, 2007 - Biométhodes that it has been granted U.S. Patent N° 7,202,086 and EP Patent N° EP1311670 for its Massive Mutagenesis® technology. Massive Mutagenesis® technology allows the generation of a large genetic diversity from any gene, mimicking natural evolution but at an accelerated laboratory scale. Massive Mutagenesis® allows the improvement of enzyme activity, stability and specificity. The technology is responsible for several successful Biométhodes projects and thereby a number of natural enzymes have been adapted for industrial use.
Massive Mutagenesis® has been adapted a number of times and one adaptation was patented and published two years ago (Saboulard et al., Biotechniques 2005), thus preceding the present revolution in synthetic biology. This technology, and its application to protein engineering, were published in several articles and have also been the subject of a chapter in a reference book... Biométhodes' Press Release (company/news) -
