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Wednesday, January 25, 2012

BIOSYNEX Immunodiagnostic has acquired 100% stake of DIMA Gesellschaft fuer Diagnostika mbH

BIOSYNEX Immunodiagnostic
January 5th, 2012 - The company BIOSYNEX Immunodiagnostic, based in France, has acquired 100% stake of DIMA Gesellschaft fuer Diagnostika mbH.

Biosynex is a French diagnostic company located in Strasbourg, one of the European capital cities at the crossroads of France and Germany. Our Research and Development laboratory and our state of the art manufacturing facility are continuously dedicated to meet news needs of the medical sector... DIMA's Press Release -

Wednesday, January 18, 2012

BioAlliance Pharma : New Achievements in the Collaboration with Its Strategic European Partner, Therabel

BioAlliance Pharma
January 04, 2012 - BioAlliance Pharma SA (Paris:BIO)(Euronext Paris - BIO), a company dedicated to specialty and orphan oncology products, today announces the achievement of the reserved capital increase and the payment of the €1 million milestone, as provided in the commercialization agreement signed with the Therabel Group for Loramyc® in Europe.

Therabel has actually subscribed for the maximum amount authorized by the General Assembly Meeting of June 29, 2011, i.e. 680.000 new shares, with a 15% premium over the last 20 business days preceding the operation (€3.65 per share).

Therabel Group

Moreover, Therabel has finalized end of December 2011 the discussions with the Italian health authorities (Agenzia Italiana del Farmaco) regarding the price and the reimbursement for Loramyc®; publication in the Italian official journal should occur shortly. In this context, BioAlliance will receive from its partner an additional payment indexed on futures sales of Loramyc® in Italy up to a maximum amount of €500.000.

BioAlliance has received more than €11 million (royalties excluded) of which €3.5 million in 2011 since the signature of its partnership agreement with Therabel. An additional €1 million payment is planned end of 2012... BioAlliance Pharma's Press Release - Communiqués de Presse BioAlliance Pharma -

Wednesday, January 11, 2012

Hemarina : ANR selects HEMO2Perf® project

Hemarina
Morlaix, Brittany, Novembre 7th, 2011 - The French National Research Agency is to fund the HEMO2Perf® project, demonstrating once again the scientific and therapeutic interest in the oxygen carriers that Hemarina develops. This funding will pave the way to the clinical use of the Hemo2Life® solution for preserving kidney grafts

Hemarina, a French biotechnology firm specialized in the research and development of marine-derived oxygen carriers for therapeutic, industrial and research applications, announced that the French National Research Agency (ANR) selected the HEMO2Perf® project under the call for proposals for the ‘Biomedical Innovation through public-private Research Partnership (RPIB)’ program. The HEMO2Perf® project teams up Hemarina, the INSERM U927 research unit “Ischemia-reperfusion in kidney transplantation” at the Poitiers University Hospital, and the Health, Life, and Agricultural Sciences Infrastructures (IBiSA) facility ‘Surgery, Experimentation, Transplantation’ in Surgères.

“The HEMO2Perf® project involves the preclinical evaluation of HEMO2Life® for the storage of kidney transplants in preservation solutions and machine perfusion systems,” explained Professor Thierry Hauet from the INSERM U927 research unit and scientific officer of the IBiSA ‘Surgery, Experimentation, Transplantation’ facility in Surgères. “The first proof of concept has already been obtained for HEMO2Life® in cold static storage. These results were published in September 2011 in The American Journal of Transplantation and show that presevation solutions supplemented with HEMO2Life® lead to better preservation and faster recovery of kidney function after transplantation (« Supplementation with a new therapeutic oxygen carrier reduces chronic fibrosis and organ dysfunction in kidney static preservation ». R Thuillier et al. American Journal of Transplantation 2011; 11(9): 1845-1860). Machine perfusion can oxygenate the kidney during organ storage. Adding an oxygen carrier such as HEMO2Life® to a machine perfusion system may also enhance the preservation of ‘borderline’ kidney grafts in perfusion machines. This is what we seek to test during the HEMO2Perf® project.”... Hemarina's Press Release - Communiqué de presse Hemarina -

Company Overview 

Hemarina SA is a privately held biotechnology company centered on the research and development of marine oxygen carriers for therapeutic and industrial applications.

Dr. Franck Zal founded Hemarina in March 2007. He is a world-renowned expert in the field of invertebrate hemoglobin and oxygen transport and has spent more than fourteen years in academic research centers (CNRS, University of California at Santa Barbara USA and University of Antwerp, Belgium) studying the relationships between the structure and function of invertebrate respiratory pigments (extracellular hemoglobin in annelids and hemocyanin in crustaceans). The discoveries arising from his research on extracellular hemoglobin in marine invertebrates and their oxygen-transport system have been patented and published in numerous scientific journals and form the crux of Hemarina’s technology

Hemarina offers products that constitute a decisive technological breakthrough in regard to current or past developments of hemoglobin-based oxygen carriers (HBOCs). Hemarina’s lead product, Hemarina M-101, is the only product under development that uses a natural, high-molecular-weight extracellular hemoglobin whose activity is totally independent of any cofactor. Furthermore, Hemarina M-101 functions in a wide range of temperatures (from 4°C to 37°C). Another major advantage of Hemarina M-101 is that it has no vasoconstrictor effect, which is frequently observed in first-generation HBOCs and responsible for significant side effects, particularly high blood pressure.

Hemarina positions itself as a R&D company focused on oxygen carrier molecules that have therapeutic and industrial applications. Our products have high-value market applications for which there are no true competitors — only potential partners. Therefore our business model revolves around finding win-win partnerships with life sciences or pharmaceutical companies who wish to incorporate Hemarina's technology in their medical devices or drug development process... Hemarina's Company Overview - L'entreprise Hemarina -

Wednesday, January 4, 2012

Eyebrain Tracker : to be used in clinical trial for Parkinson’s therapy

EyeBrain
December xx, 2011 - EyeBrain’s eye-tracking device will be used to evaluate the effects of levodopa on patients’ motricity -

EyeBrain, a company developing medical devices for the early diagnosis of neurological diseases, announces that its EyeBrain Tracker device is being used in a clinical trial exploring the dyskinesia induced by treating patients suffering from idiopathic Parkinson’s disease with levodopa.

The endpoint of the trial is to find biomarkers for the late-onset complications of a treatment regime using levodopa (BIODYS). This compound, which is naturally transformed into dopamine in the brain, is one of the only drugs available for slowing the effects of Parkinson’s disease. However, over time, it induces dyskinesia in these patients, which takes the form of abnormal movements primarily affecting the face (tongue, lips, jaw) and extending as far as the arms and legs.

Altogether, 30 people will be enrolled on the trial. Half of them will be Parkinson’s sufferers who have been treated with levodopa and have developed dyskinesia, while the other half will consist of healthy subjects who will be used as a control group...

[...]

...About EyeBrain 

EyeBrain manufactures medical devices for the early diagnosis of neurological diseases. These devices are based on the movement of the eyes, and they make it possible to test specific regions of the brain by recording and analyzing eye movements using very sophisticated algorithms developed by the company. EyeBrain’s devices fill a gap in neurological diagnostics. For the first time, clinicians can rely on a simple set of eye movement parameters to differentiate between very similar syndromes, such as progressive supra-nuclear paralysis (PSP) and cortico-basal degeneration (CBD). The test is easy to carry out, non-invasive, and the results are available in less than 20 minutes for a small cost... [PDF] EyeBrain's Press Release - PDF du communiqué de presse de EyeBrain -