Evry, France, April 13, 2010 - IntegraGen SA, a French biotechnology company dedicated to gene discovery, announced the publication of the results of a collaborative study reporting the use of a combined analysis of multiple genetic variants in a genetic score to help identify individuals at high risk of developing autism.The study, entitled “Assessing the Impact of a Combined Analysis of Four Common Low-risk Genetic Variants on Autism Risk” appears in Molecular Autism, a peer-reviewed journal that publishes research on the molecular basis of autism and related neurodevelopmental conditions.
Based on an analysis of samples from two separate genetic sample collections which included over 450 families and nearly 1,000 children affected by autism, the authors report that the accumulation of multiple risk alleles in a genetic score is a useful strategy for assessing the risk of autism in children who have older siblings affected by autism. The authors suggest that this approach may be better than studying single polymorphisms for identifying subgroups of individuals with significantly greater risk of autism...
[...]
...About IntegraGen
IntegraGen is a biotechnology company dedicated to gene discovery with the goal of developing molecular diagnostic products and services that provide clinicians with new tools to personalize diagnosis, treatment, and therapy. IntegraGen, and its wholly owned U.S. subsidiary IntegraGen, Inc., are focused on the prevention and proactive management of complex debilitating diseases, and dedicated to addressing the needs of patients, clinicians, and advocacy groups. IntegraGen’s Genetic Services Business, based in Evry, France, also provides state of the art Genotyping Services to the research community. With discovery and intellectual property focused on Autism, Oncology, IntegraGen’s Core Strategy is to deliver a portfolio of high-value molecular diagnostic products and services that drive personalized healthcare solutions for complex diseases... [PDF] IntegraGen's Press Release -
